| Player | Tm | Pos | Gm | GS | W | L | Sv | CG | Sh | IP | H | R | ER | HR | BB | K | ERA | WHP |
| Papelbon, Jonathan |
Bos |
RP |
45 |
1 |
3 |
2 |
24 |
0 |
0 |
53 |
34 |
10 |
10 |
4 |
15 |
64 |
1.63 |
0.93 |
| Saito, Takashi |
LaN |
RP |
45 |
0 |
3 |
1 |
21 |
0 |
0 |
47 |
27 |
10 |
9 |
3 |
12 |
62 |
1.77 |
0.82 |
| Nathan, Joe |
Min |
RP |
67 |
0 |
6 |
2 |
39 |
0 |
0 |
70 |
46 |
16 |
16 |
4 |
19 |
89 |
2.07 |
0.93 |
| Rivera, Mariano |
NyA |
RP |
67 |
0 |
5 |
4 |
36 |
0 |
0 |
75 |
60 |
20 |
17 |
3 |
14 |
70 |
2.09 |
0.98 |
| Wagner, Billy |
NyN |
RP |
70 |
0 |
3 |
2 |
37 |
0 |
0 |
72 |
53 |
20 |
17 |
6 |
21 |
87 |
2.12 |
1.02 |
| Gardner, Lee |
Fla |
RP |
22 |
0 |
1 |
1 |
1 |
0 |
0 |
27 |
28 |
9 |
7 |
1 |
7 |
19 |
2.22 |
1.28 |
| Okajima, Hideki |
Bos |
RP |
22 |
0 |
1 |
1 |
2 |
0 |
0 |
23 |
17 |
6 |
6 |
2 |
6 |
21 |
2.22 |
0.97 |
| Ryan, BJ |
Tor |
RP |
46 |
0 |
1 |
3 |
26 |
0 |
0 |
49 |
34 |
13 |
12 |
3 |
17 |
63 |
2.22 |
1.05 |
| Moylan, Peter |
Atl |
RP |
32 |
0 |
2 |
1 |
0 |
0 |
0 |
35 |
28 |
12 |
9 |
2 |
12 |
26 |
2.23 |
1.13 |
| Perez, Rafael |
Cle |
RP |
21 |
0 |
0 |
1 |
0 |
0 |
0 |
24 |
17 |
7 |
6 |
2 |
7 |
26 |
2.25 |
1.00 |
| Hermanson, Dustin |
N/A |
RP |
21 |
0 |
1 |
1 |
11 |
0 |
0 |
21 |
17 |
7 |
5 |
2 |
6 |
13 |
2.29 |
1.11 |
| Gonzalez, Mike |
Atl |
RP |
41 |
0 |
2 |
2 |
10 |
0 |
0 |
40 |
31 |
10 |
10 |
1 |
23 |
45 |
2.31 |
1.34 |
| Putz, JJ |
Sea |
RP |
68 |
0 |
5 |
2 |
26 |
0 |
0 |
70 |
51 |
19 |
18 |
6 |
16 |
77 |
2.37 |
0.97 |
| Rodriguez, Francisco |
LaA |
RP |
66 |
0 |
3 |
3 |
44 |
0 |
0 |
69 |
49 |
19 |
18 |
5 |
31 |
93 |
2.39 |
1.16 |
| Soria, Joakim |
KC |
SP |
21 |
0 |
1 |
1 |
6 |
0 |
0 |
23 |
15 |
7 |
6 |
1 |
6 |
25 |
2.48 |
0.94 |
| Clemens, Roger |
N/A |
SP |
23 |
23 |
9 |
7 |
0 |
0 |
0 |
141 |
113 |
46 |
40 |
9 |
41 |
118 |
2.53 |
1.09 |
| Corpas, Manuel |
Col |
RP |
38 |
0 |
2 |
1 |
6 |
0 |
0 |
37 |
33 |
11 |
10 |
3 |
9 |
28 |
2.54 |
1.15 |
| Betancourt, Rafael |
Cle |
RP |
57 |
0 |
4 |
3 |
2 |
0 |
0 |
67 |
53 |
20 |
19 |
5 |
12 |
67 |
2.58 |
0.98 |
| Street, Huston |
Oak |
RP |
61 |
0 |
5 |
2 |
25 |
0 |
0 |
66 |
51 |
22 |
19 |
4 |
17 |
67 |
2.59 |
1.03 |
| Feliciano, Pedro |
NyN |
RP |
47 |
0 |
3 |
1 |
1 |
0 |
0 |
41 |
34 |
14 |
12 |
2 |
17 |
38 |
2.61 |
1.24 |
| Zumaya, Joel |
Det |
RP |
30 |
0 |
3 |
2 |
1 |
0 |
0 |
39 |
26 |
12 |
11 |
3 |
20 |
41 |
2.64 |
1.19 |
| Soriano, Rafael |
Atl |
RP |
44 |
0 |
1 |
2 |
4 |
0 |
0 |
46 |
32 |
14 |
14 |
6 |
12 |
48 |
2.65 |
0.96 |
| Neshek, Pat |
Min |
RP |
35 |
0 |
4 |
1 |
0 |
0 |
0 |
36 |
22 |
11 |
11 |
4 |
11 |
42 |
2.69 |
0.93 |
| Hoffman, Trevor |
SD |
RP |
62 |
0 |
2 |
4 |
44 |
0 |
0 |
59 |
50 |
20 |
18 |
4 |
13 |
49 |
2.69 |
1.07 |
| Isringhausen, Jason |
StL |
RP |
62 |
0 |
3 |
3 |
35 |
0 |
0 |
61 |
44 |
20 |
18 |
6 |
31 |
52 |
2.72 |
1.24 |
| Liriano, Francisco |
Min |
P |
11 |
7 |
4 |
2 |
0 |
0 |
0 |
48 |
36 |
15 |
15 |
4 |
13 |
59 |
2.75 |
1.02 |
| Duchscherer, Justin |
Oak |
RP |
45 |
0 |
4 |
3 |
5 |
0 |
0 |
52 |
46 |
17 |
16 |
5 |
12 |
50 |
2.77 |
1.11 |
| Cameron, Kevin |
SD |
RP |
16 |
0 |
1 |
0 |
0 |
0 |
0 |
19 |
18 |
8 |
6 |
0 |
12 |
17 |
2.79 |
1.57 |
| Speier, Justin |
LaA |
RP |
58 |
0 |
2 |
2 |
0 |
0 |
0 |
56 |
44 |
18 |
17 |
7 |
16 |
53 |
2.80 |
1.07 |
| Cordero, Chad |
Was |
RP |
73 |
0 |
4 |
4 |
38 |
0 |
0 |
74 |
63 |
27 |
23 |
10 |
23 |
64 |
2.80 |
1.16 |
| Otsuka, Akinori |
N/A |
RP |
54 |
0 |
2 |
4 |
12 |
0 |
0 |
51 |
45 |
18 |
16 |
2 |
18 |
43 |
2.82 |
1.23 |
| Wickman, Bob |
N/A |
RP |
59 |
0 |
1 |
5 |
33 |
0 |
0 |
55 |
55 |
21 |
18 |
5 |
18 |
40 |
2.87 |
1.32 |
| Ayala, Luis |
Was |
RP |
37 |
0 |
3 |
3 |
1 |
0 |
0 |
38 |
39 |
13 |
12 |
4 |
9 |
23 |
2.87 |
1.27 |
| Harden, Rich |
Oak |
SP |
13 |
11 |
5 |
2 |
0 |
1 |
0 |
66 |
47 |
24 |
22 |
5 |
27 |
66 |
2.94 |
1.12 |
| Santana, Johan |
NyN |
SP |
33 |
33 |
17 |
9 |
0 |
2 |
1 |
228 |
183 |
81 |
76 |
26 |
48 |
239 |
2.99 |
1.01 |
| Broxton, Jonathan |
LaN |
RP |
55 |
0 |
3 |
2 |
2 |
0 |
0 |
57 |
48 |
22 |
19 |
4 |
23 |
73 |
3.00 |
1.25 |
| Guerrier, Matt |
Min |
RP |
52 |
0 |
1 |
2 |
1 |
0 |
0 |
76 |
73 |
27 |
25 |
8 |
22 |
50 |
3.00 |
1.25 |
| Howry, Bob |
ChN |
RP |
80 |
0 |
6 |
5 |
5 |
0 |
0 |
77 |
65 |
27 |
26 |
7 |
17 |
64 |
3.01 |
1.07 |
| Carpenter, Chris |
StL |
SP |
22 |
22 |
12 |
5 |
0 |
4 |
2 |
156 |
136 |
56 |
52 |
13 |
32 |
133 |
3.02 |
1.07 |
| Meredith, Cla |
SD |
RP |
43 |
0 |
3 |
2 |
0 |
0 |
0 |
44 |
43 |
17 |
15 |
3 |
9 |
32 |
3.02 |
1.20 |
| Player | Tm | Pos | Gm | GS | W | L | Sv | CG | Sh | IP | H | R | ER | HR | BB | K | ERA | WHP |
| Oswalt, Roy |
Hou |
SP |
34 |
33 |
16 |
9 |
0 |
2 |
0 |
224 |
228 |
80 |
76 |
17 |
49 |
168 |
3.04 |
1.23 |
| Riske, David |
Mil |
RP |
55 |
0 |
2 |
3 |
2 |
0 |
0 |
62 |
52 |
22 |
21 |
8 |
20 |
43 |
3.06 |
1.16 |
| Linebrink, Scott |
ChA |
RP |
72 |
0 |
7 |
4 |
1 |
0 |
0 |
73 |
64 |
27 |
25 |
8 |
23 |
63 |
3.06 |
1.21 |
| Capps, Matt |
Pit |
RP |
55 |
0 |
4 |
3 |
6 |
0 |
0 |
54 |
50 |
20 |
19 |
6 |
9 |
41 |
3.09 |
1.09 |
| Lindstrom, Matt |
Fla |
RP |
24 |
0 |
1 |
1 |
0 |
0 |
0 |
22 |
22 |
9 |
8 |
1 |
7 |
21 |
3.09 |
1.30 |
| Helling, Rick |
N/A |
RP |
12 |
3 |
1 |
1 |
0 |
0 |
0 |
28 |
21 |
10 |
10 |
3 |
11 |
25 |
3.11 |
1.15 |
| Shields, Scot |
LaA |
RP |
74 |
0 |
7 |
8 |
4 |
0 |
0 |
85 |
66 |
33 |
30 |
7 |
31 |
86 |
3.14 |
1.15 |
| Peavy, Jake |
SD |
SP |
32 |
32 |
14 |
9 |
0 |
2 |
1 |
209 |
173 |
77 |
73 |
18 |
60 |
224 |
3.15 |
1.11 |
| Fuentes, Brian |
Col |
RP |
69 |
0 |
3 |
5 |
27 |
0 |
0 |
67 |
52 |
25 |
23 |
7 |
28 |
73 |
3.15 |
1.19 |
| Flores, Ron |
N/A |
RP |
18 |
0 |
0 |
1 |
0 |
0 |
0 |
18 |
17 |
7 |
6 |
2 |
7 |
14 |
3.17 |
1.37 |
| Reyes, Dennys |
Min |
RP |
51 |
0 |
3 |
1 |
0 |
0 |
0 |
41 |
42 |
17 |
14 |
2 |
23 |
35 |
3.17 |
1.59 |
| Sweeney, Brian |
N/A |
RP |
12 |
0 |
1 |
0 |
1 |
0 |
0 |
19 |
18 |
7 |
7 |
2 |
5 |
8 |
3.21 |
1.23 |
| Webb, Brandon |
Ari |
SP |
33 |
33 |
16 |
10 |
0 |
3 |
2 |
233 |
218 |
93 |
83 |
16 |
60 |
181 |
3.21 |
1.19 |
| Littleton, Wes |
Tex |
RP |
23 |
0 |
2 |
1 |
1 |
0 |
0 |
28 |
24 |
10 |
10 |
3 |
10 |
14 |
3.21 |
1.19 |
| Halladay, Roy |
Tor |
SP |
27 |
27 |
15 |
5 |
0 |
5 |
1 |
195 |
186 |
74 |
70 |
15 |
33 |
126 |
3.21 |
1.12 |
| Ray, Chris |
Bal |
RP |
48 |
0 |
3 |
4 |
16 |
0 |
0 |
49 |
38 |
20 |
18 |
7 |
21 |
46 |
3.22 |
1.20 |
| Smoltz, John |
Atl |
SP |
33 |
33 |
15 |
8 |
0 |
2 |
1 |
222 |
209 |
85 |
80 |
20 |
52 |
192 |
3.23 |
1.17 |
| Sanchez, Anibal |
Fla |
SP |
8 |
8 |
4 |
1 |
0 |
1 |
0 |
48 |
44 |
19 |
17 |
4 |
22 |
29 |
3.25 |
1.38 |
| Timlin, Mike |
Bos |
RP |
66 |
0 |
5 |
3 |
8 |
0 |
0 |
66 |
70 |
26 |
24 |
5 |
17 |
40 |
3.26 |
1.31 |
| Bradford, Chad |
Bal |
RP |
60 |
0 |
3 |
3 |
1 |
0 |
0 |
50 |
55 |
20 |
18 |
1 |
11 |
28 |
3.26 |
1.33 |
| Walker, Jamie |
Bal |
RP |
68 |
0 |
2 |
2 |
2 |
0 |
0 |
52 |
51 |
21 |
19 |
6 |
13 |
36 |
3.27 |
1.22 |
| Heilman, Aaron |
NyN |
RP |
69 |
2 |
5 |
5 |
2 |
0 |
0 |
94 |
77 |
38 |
34 |
6 |
28 |
81 |
3.27 |
1.13 |
| Jenks, Bobby |
ChA |
RP |
55 |
0 |
2 |
3 |
29 |
0 |
0 |
58 |
48 |
22 |
21 |
3 |
20 |
62 |
3.28 |
1.18 |
|
| | |